Pharmaceutical Sci&Tech

Basics of Biomarker

  What is a Biomarker? The term “biomarker” is composed of “biological” and “marker.” Different disciplines have slightly different definitions for biomarkers, but the general concept is consistent. The National Institutes of Health (NIH) in the...
Chemical Industry Pharmaceutical Regulation

The Ames Test: Unraveling Mutagenic Potential

The Ames test, a cornerstone of genetic toxicology, serves as a crucial tool for identifying potential mutagens and carcinogens. Several regulatory guidelines govern the conduct and interpretation of Ames tests, including OECD Test Guideline 471: This guideline provides...