Month: November 2025
Biotech
Pharmaceutical
Sci&Tech
A Comprehensive Analysis of ADME Challenges for PROTACs
Proteolysis-targeting chimera (PROTAC) molecules have emerged as a revolutionary approach in drug discovery, offering the potential to selectively degrade target proteins. However, their design, characterized by a bivalent structure comprising a target protein-binding ligand (warhead), an E3...
Chemical
GLP
Pharmaceutical
Regulation
Sci&Tech
New Approach Methodologies for Chemical Safety Assessment
Within fields like toxicology and drug development, embracing New Approach Methodologies (NAMs) is no longer optional but crucial for professionals seeking to remain at the forefront of their disciplines. Understanding and applying these innovative, human-relevant techniques...