Day: November 17, 2025
Biotech
Pharmaceutical
Sci&Tech
A Comprehensive Analysis of ADME Challenges for PROTACs
Proteolysis-targeting chimera (PROTAC) molecules have emerged as a revolutionary approach in drug discovery, offering the potential to selectively degrade target proteins. However, their design, characterized by a bivalent structure comprising a target protein-binding ligand (warhead), an E3...
