Month: January 2026
Chemical
Pharmaceutical
Sci&Tech
Aptamer Drug Development Status and Pipeline
The development of therapeutic aptamers has evolved from a niche technology challenged by pharmacokinetic (PK) issues (stability and renal clearance) to a robust platform. While only two RNA aptamers are currently FDA-approved, the pipeline contains dozens...
Industry
Pharmaceutical
Regulation
Sci&Tech
PBPK Modeling -The Computational Engine Driving Modern Drug Safety
The pharmaceutical industry is undergoing a paradigm shift, moving towards New Approach Methodologies (NAMs) to reduce reliance on traditional animal models. At the forefront of this shift is Physiologically Based Pharmacokinetic (PBPK) modeling, a mechanism-driven computational approach...