Author: ChemRealm
Pharmaceutical
Regulation
What are drugs made in the US
There’s no strict legal definition of “Made in USA” for drugs enforced by the FDA. However, we can still refer to some regulation requirements to help understand how they are generally categorized in relation to their origin: 1....
Biotech
GLP
Industry
Pharmaceutical
Regulation
Understanding about the FDA’s Embrace of New Approach Methodologies
In a landmark decision signaling a paradigm shift in pharmaceutical safety assessment, the U.S. Food and Drug Administration (FDA) announced on April 10, 2025, a plan to phase out the requirement for animal testing in the...
Pharmaceutical
Sci&Tech
Why Nav1.8 inhibitor is non-addictive pain killer
Journavx (VX-548, Suzetrigine) was approved in 2025 as the only new non-opoid painkiller in the past two decades. As we know it is a Nav1.8 inibitor, here we explain why Nav1.8 inhibitors won’t cause addiction(Disclaimer: based on the...
Industry
Pharmaceutical
The “NewCo” Revolution: Fueling Chinese Biotech’s Global Ascent
China’s biotech sector is transforming through the “NewCo” model, a strategic spin-off approach designed to accelerate innovation and secure international investment. This model involves creating independent companies (“NewCos”) that house promising drug development assets, effectively decoupling...
Molecule Digest
Pharmaceutical
Molecule Digest: Suzetrigine
What is Suzetrigine Suzetrigine is the generic drug name for brand drug, Journavx. In Jan. 2025, FDA approved Vertec Pharmaceuticals to market the Journavx, a 50 mg tablet to treat short-term (acute) moderate to severe pain. As an...
Industry
Pharmaceutical
Sci&Tech
Combination Drugs-Synergistic Therapy
A combination drug, or a fixed-dose combination (FDC), is a medication that includes two or more active ingredients combined into a single dosage form. Synergy occurs when drugs utilized in combination lead to a combined total effect...
Industry
Pharmaceutical
An article to learn the Chinese new drug industry
We all heard the Chinese biotechs are booming. I am always wondering if there are statiscal data to learn about the innovative drug development in China. Recently, a research article titled “Chinese innovative drug R&D trends in...
Industry
Pharmaceutical
The status quo of antitivrus drugs
Developing effective antiviral drugs is a complex task due to the rapid evolution of viruses. Viruses can develop resistance to antiviral drugs, making it necessary to continually develop new treatments. Additionally, viruses often rely on host...
Chemical
Molecule Digest
Pharmaceutical
The Medicinal Value of D-Amino Acids
Despite the dominance of L-amino acids, D-amino acids are not mere curiosities. They have been found in various biological systems, often playing critical roles. D-Amino Acids in Nature Previously referred to as “unnatural” amino acids, D-amino...
Industry
Pharmaceutical
PopSci
Are drugs too expensive?
The question of whether prescription drugs are too expensive is a complex one. While there’s no simple answer, it’s clear that the cost of many medications has risen dramatically in recent years. This has led...