Author: ChemRealm
Industry
Pharmaceutical
Sci&Tech
Combination Drugs-Synergistic Therapy
A combination drug, or a fixed-dose combination (FDC), is a medication that includes two or more active ingredients combined into a single dosage form. Synergy occurs when drugs utilized in combination lead to a combined total effect...
Industry
Pharmaceutical
An article to learn the Chinese new drug industry
We all heard the Chinese biotechs are booming. I am always wondering if there are statiscal data to learn about the innovative drug development in China. Recently, a research article titled “Chinese innovative drug R&D trends in...
Industry
Pharmaceutical
The status quo of antitivrus drugs
Developing effective antiviral drugs is a complex task due to the rapid evolution of viruses. Viruses can develop resistance to antiviral drugs, making it necessary to continually develop new treatments. Additionally, viruses often rely on host...
Chemical
Molecule Digest
Pharmaceutical
The Medicinal Value of D-Amino Acids
Despite the dominance of L-amino acids, D-amino acids are not mere curiosities. They have been found in various biological systems, often playing critical roles. D-Amino Acids in Nature Previously referred to as “unnatural” amino acids, D-amino...
Industry
Pharmaceutical
PopSci
Are drugs too expensive?
The question of whether prescription drugs are too expensive is a complex one. While there’s no simple answer, it’s clear that the cost of many medications has risen dramatically in recent years. This has led...
Industry
Pharmaceutical
21 FDA approved small molecular drugs in 2024
As Christmas is approaching, 2024 marked a significant year for drug development, with the FDA approving numerous novel therapies across various therapeutic areas. Rare diseases experienced a transformative year in 2024, with drugs accounting for 23.8% of...
Industry
Pharmaceutical
A new drug project manager’s responsibility
As a new drug project manager, the primary task is to develop a detailed project plan based on the project’s standard operating procedures (SOPs) and stakeholder registry after initiating a new drug development project. In order for beginner to understand the...
Chemical
PopSci
The rising concern of PFAS
PFAS (Per- and Polyfluoroalkyl Substances) are a group of man-made chemicals that are resistant to degradation, meaning they can persist in the water, soil, and air in many regions for a long time. Due to their widespread use...
Industry
Pharmaceutical
Boron in the spotlight-Drugs that containing boron
The importance of boron to med chem is undeniable. It is also crowned with Nobel prize in 1979 by recognizing prof. Herbert C. Brown’s contribution to boron chemistry. However, the incorporation of boron in durg molecules...
GLP
Pharmaceutical
Regulation
What non-clinical safety test are used to support drug indicated for pregnant women?
Due to ethical concerns, testing medications directly on pregnant women is strictly limited. Therefore, non-clinical safety tests play a crucial role in assessing potential risks associated with a drug for pregnant women and the developing fetus. Some...