Category: Sci&Tech
Chemical
Pharmaceutical
Sci&Tech
what is drug-like properties
Drug-like properties, also known as druglikeness, are a crucial concept in the pharmaceutical world. They describe the inherent characteristics of a molecule that influence its potential for successful drug development. In 2000, Christopher A. Lipinski proposed...
Biotech
Pharmaceutical
Sci&Tech
Drug discovery: is target-based superior to phenotypic model?
In current pharmaceutical sciences, when we talk about innovative drug discovery, we should think of target-based drug discovery, which is to design synthetic drugs based on a target. Then, have we thought about how efficient this...
Sci&Tech
Basics of Radiopharmaceuticals
What is radiopharmaceutical? Radiopharmaceuticals include a group of radioactive agents used for either diagnostic or therapeutic interventions. Radiopharmaceutical therapy is defined by the delivery of radioactive atoms to disease-associated targets. But do not be confused with...
Sci&Tech
KRAS is no longer undruggable
A while ago, I wrote simply about the KRAS gene related research trend. It is official!! FDA grants FIRST accelerated approval to sotorasib for KRAS G12C mutated NSCLC. See the follow link for report by Fierce...
Industry
Sci&Tech
Program Overview: Small Business Innovation Research (SBIR) & Small Business Technology Transfer program (STTR)
When you come up a innovative idea that potentially can change the current tech market and enhance people’s life, why not chase your dream and bring your idea to market. Of course, you need funding to...
Industry
Sci&Tech
Positron emission tomography (PET) drugs, pipelines and market
Positron emission tomography (PET) drugs, pipelines and market Positron emission tomography (PET) is a nuclear medicine imaging technique that produces a three-dimensional image or picture of functional processes in the body. Drugs Used to Treat Positron...
Industry
Sci&Tech
KRAS gene related research trends
The KRAS gene provides instructions for making K-Ras protein that is part of a signaling pathway known as the RAS/MAPK pathway. The protein relays signals from outside the cell to the cell’s nucleus. These signals instruct...
Industry
Sci&Tech
Gist of funding trend for bioconjugation technology in academia
Bioconjugation is a chemical strategy used widely in many aspect of biological research. It usually ligate two molecules together with at least one biomolecules. The development of click chemistry advances the application of bioconjugation in many...