Chemical

Chemical Industry Pharmaceutical Regulation

The Ames Test: Unraveling Mutagenic Potential

The Ames test, a cornerstone of genetic toxicology, serves as a crucial tool for identifying potential mutagens and carcinogens. Several regulatory guidelines govern the conduct and interpretation of Ames tests, including OECD Test Guideline 471: This guideline provides...

Chemical Molecule Digest Pharmaceutical

The Medicinal Value of D-Amino Acids

Despite the dominance of L-amino acids, D-amino acids are not mere curiosities. They have been found in various biological systems, often playing critical roles. D-Amino Acids in Nature Previously referred to as “unnatural” amino acids, D-amino...

Chemical PopSci

The rising concern of PFAS

PFAS (Per- and Polyfluoroalkyl Substances) are a group of man-made chemicals that are resistant to degradation, meaning they can persist in the water, soil, and air in many regions for a long time. Due to their widespread use...

Chemical PopSci

Can you really have “Pure” chemicals

Is it possible to completely purify a chemical? This is a question that many people have wondered about at some point. The answer, unfortunately, is no. It is not possible to completely purify a chemical. Why...

Chemical Pharmaceutical Sci&Tech

what is drug-like properties

Drug-like properties, also known as druglikeness, are a crucial concept in the pharmaceutical world. They describe the inherent characteristics of a molecule that influence its potential for successful drug development. In 2000, Christopher A. Lipinski proposed...

Chemical Industry Regulation

What permits are needed to start a Chemical research laboratory?

The permits you need to start a chemical research lab will vary depending on the size and type of lab, as well as the local regulations. However, some common permits that may be required include: Building...

Chemical Pharmaceutical Regulation

What are Nitrosamine Impurities in Drugs

Nitrosamine, formally known as N-nitrosoamine, is a class of organic molecules with the above core structure. These type of chemicals are believed carcinogenic due to their potential as alylating reagents inside cells, which will cause cancer....