Author: ChemRealm
Chemical
Pharmaceutical
Sci&Tech
what is drug-like properties
Drug-like properties, also known as druglikeness, are a crucial concept in the pharmaceutical world. They describe the inherent characteristics of a molecule that influence its potential for successful drug development. In 2000, Christopher A. Lipinski proposed...
Biotech
Industry
The biotech company numbers by the country
First of all, this article is just a recap of the OECD statistics. If you are interested in the topic, I would recommend a nice article at Labbiotech. The OECD’s latest update on key biotech indicators highlights rising...
Biotech
Pharmaceutical
Sci&Tech
Drug discovery: is target-based superior to phenotypic model?
In current pharmaceutical sciences, when we talk about innovative drug discovery, we should think of target-based drug discovery, which is to design synthetic drugs based on a target. Then, have we thought about how efficient this...
cGMP
Industry
Pharmaceutical
The importance of CMC in Drug Development
Drug development is a long, expensive, and risky process. The drug development process mainly includes: Target identification, Discovery, Preclinical pharmaceutical research (IND), Clinical trials (Phases I, II, and III) , NDA/BLA and comercial Launch. CMC (Chemistry Manufacturing & Control) is a very important part of drug approval....
Industry
Pharmaceutical
PopSci
Test BARD for the topic of Weight loss Drug
Recently, the weight loss drug is at the spotlight. I just want to test how Google Bard will tell me about this topic. So I got three questions and three answers. It only helps understand the...
GLP
Regulation
The synopsis of GLP
Suddenly, a though occurs in my head how to explain Good Laboratory Practice (GLP) to a beginner. Many people only need to know the key points of GLP. They do not have interests or are not...
Biotech
Industry
Pharmaceutical
What are the FDA approved drugs for Alzheimer disease
There are currently five FDA-approved drugs for the treatment of Alzheimer’s disease: Donepezil (Aricept) is a cholinesterase inhibitor that helps to increase the levels of acetylcholine in the brain. Acetylcholine is a neurotransmitter that is involved in...
Industry
Pharmaceutical
Regulation
Whether human research can be conducted without IND
It is a a simple question, but people usually forget to ask when they enter the pharmaceutical industry. Yes, human research can be conducted without an IND(investigational new drug) in certain cases. The FDA has a...
Chemical
Industry
Regulation
What permits are needed to start a Chemical research laboratory?
The permits you need to start a chemical research lab will vary depending on the size and type of lab, as well as the local regulations. However, some common permits that may be required include: Building...
Pharmaceutical
Regulation
One Minute to Learn the Gist of Investigational New Drug (IND) Application
This is a brief note of the IND application intended for peers who just started learning the IND with very little understanding. Please refer to FDA website for more detail, but it will take some time....